New Portfolio

Patients with RDEB are at an increased risk of an aggressive squamous cell carcinoma (SCC) which is usually fatal. This project ...

Study of the Safety, Tolerability, and Efficacy of an iPS Cell-based Therapy for RDEB Delivered with a Spray-on-Skin Device ...

PASTE-Mediated Superexon Replacement of COL7A1 as a Treatment for Dystrophic Epidermolysis Bullosa ...

siRNA-mediated allele-specific inhibition of mutant KRT5 and KRT14 transcripts carrying frequent dominant mutations in epidermolysis bullosa simplex (EBS) ...

Exon skipping approach to RDEB, with the aim to create a shorter but functional Collagen VII protein ...

My Day by Sohana At 8am I wake up to take five different medications and allow them to set in ...

Mornings are getting tougher the older she gets. Sleep is constantly broken throughout the night when she is uncomfortable or ...

Our little boy Albi was born with severe Recessive Dystrophic Epidermolysis Bullosa ...

Gabrielius’ morning begins before 7AM, while he is still asleep. We start by changing the dressings on his legs. When ...

Mason gets up for school about 7am when his respite nurse leaves. We will do any dressings that need doing ...

I met Hon back in 2009. He was busy working for Whizz-Kids, teaching children how to use their wheelchairs. We ...

By Karen, Dylan's mum After a healthy and low risk pregnancy, our beautiful son Dylan was born in June 2017 ...

I grew up in a family where I was the first to be diagnosed with EB Simplex (EBS). I never ...

Kindler syndrome is a rare type of EB that results from mutations in the FERMT1 gene. From early infancy, people ...

Epidermolysis Bullosa Simplex (EBS) Epidermolysis Bullosa Simplex is the most common type of EB, accounting for around 70% of cases ...

Junctional Epidermolysis Bullosa (JEB) Junctional epidermolysis bullosa is recessively inherited and involves mutations in the genes for several components of ...

Dystrophic EB (DEB) Dystrophic EB can be either dominantly or recessively inherited and involves defects in Type VII collagen. Blisters ...

Isla's Day We turn off Isla’s feeding pump and give her her morning meds at about 7:30am and then wake her as ...

Testing the in vivo efficacy of base and prime editing in primary fibroblasts and in a 3D skin model of ...

Rigosertib for recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma ...

My son was not diagnosed with EB at birth. We noticed his first blisters at 4 months old. I had ...

When I was born in 1972, not much about EB was known. No one else in my family had it ...

Living with EB has taught me how to be strong and tolerate severe pain. Therefore, it will not stop me ...

Finally, just before I turned 28, I was diagnosed with EB. And my world opened up! I was finally part ...

I gave the faulty gene to my lovely son. He is in constant pain but smiles through it - he ...

Testing the efficacy of genomic base editing in dystrophic epidermolysis bullosa primary fibroblasts ...

Development of a topical gene-editing treatment to restore Collagen VII ...

Combined respiratory epithelial cell and gene therapy for amelioration of respiratory symptoms in children with Junctional Epidermolysis Bullosa ...

Pre-clinical and clinical trial for using gene-edited skin in Recessive Dystrophic Epidermolysis Bullosa ...

A nanoneedle bandage for topical intracellular COL7A1 gene therapy to accelerate wound healing in Recessive Dystrophic Epidermolysis Bullosa ...

Double blind placebo controlled study of mesenchymal intravenous stromal cell infusions in children with Recessive Dystrophic Epidermolysis Bullosa ...

Development of a topical gel formulation of decorin to reduce fibrosis ...

Development of IV-administered siRNAs targeting mutant KRT5 and KRT1 in EB Simplex ...

Development of an oral formulation of the peptide angiotensin-(1-7) to reduce fibrosis ...

Phase I/II ex vivo gene therapy clinical trial for RDEB using autologous skin equivalent grafts genetically corrected with a COL7A1-encoding ...

Gene editing for Epidermolysis Bullosa ...

Epidermolysis Bullosa Therapeutic Reprogramming Consortium ...

Next generation genome editing for Recessive Dystrophic Epidermolysis Bullosa ...

Stem cell regeneration of the ocular surface in Recessive Dystrophic Epidermolysis Bullosa ...

Deep sequencing Recessive Dystrophic Epidermolysis Bullosa squamous cell carcinoma ...

Phase I study of lentiviral-mediated COL7A1 gene-modified autologous fibroblasts in adults with Recessive Dystrophic Epidermolysis Bullosa ...

Mensenchymal stromal cells engineered to express Collagen VII for the treatment of Recessive Dystrophic Epidermolysis Bullosa ...

A phase I/II study to evaluate allogeneic mesenchymal stromal cells for the treatment of skin disease in adults with Recessive ...

Limbal stem cells for treatment of corneal wounds in Epidermolysis Bullosa Lay summary The cornea, the transparent outer surface of ...

A TALEN-based approach to developing safer, more effective treatments for people with Epidermolysis Bullosa ...

Clinical trial of mesenchymal stromal cells in Recessive Dystrophic Epidermolysis Bullosa ...