Archive

30 September, 2025

NanoCure

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text css=".vc_custom_1759225222550{padding-bottom: 30px !important;}"] NanoCure: A Medical Grade Nanoneedle Bandage for Topical COL7A1 Gene Therapy [ninja_tables id='20992'] Lay summary Supported by Cure EB (NanoCol), our team has developed NanoCure, a bandage designed to improve wound healing in recessive dystrophic epidermolysis bullosa (RDEB)....

19 May, 2025

ELK-003

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text css=".vc_custom_1747656706954{padding-bottom: 30px !important;}"] ELK-003 - an opthalmic solution for the treatment of corneal abrasions associated with epidermolysis bullosa [ninja_tables id="20545"] Investment summary Eliksa Therapeutics is developing ELK-003, a topical eye drop with the potential to both prevent and treat painful corneal...

29 January, 2025

mRNA-based base editing

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text css=".vc_custom_1738156164924{padding-bottom: 30px !important;}"] Evaluation of long-term effect on skin homeostasis and regeneration in a RDEB mouse model using different delivery methods of LNPs encapsulating mRNA-based base editing approach. [ninja_tables id="20392"] Lay summary Over the last 30 years, we have learned that...

27 January, 2025

Therapy for JEB Airway Disease

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text css=".vc_custom_1737023346987{padding-bottom: 30px !important;}"] Towards cell and gene therapy for Junctional Epidermolysis Bullosa airway disease [ninja_tables id="20307"] Lay summary There has been little research into airway symptoms in Junctional EB, limiting the therapeutic options available for children who develop airway disease. Our...

15 January, 2025

Nova Anchora

Development of NvA-011, a recombinant version of collagen VII for topical application in Dystrophic EB....

21 November, 2024

Base & Prime Editing for RDEB

The project aims to develop a strategy that could be used to treat a significant subset of RDEB patients carrying selected mutations....

28 February, 2024

Nonsense Tx

Nonsense Tx reading through disease causing nonsense codons...

13 December, 2023

PASTE gene therapy in DEB

PASTE-Mediated Superexon Replacement of COL7A1 as a Treatment for Dystrophic Epidermolysis Bullosa...

01 September, 2022

Editing of RDEB fibroblasts

Testing the in vivo efficacy of base and prime editing in primary fibroblasts and in a 3D skin model of dystrophic epidermolysis bullosa...

01 April, 2021

Base editing of RDEB fibroblasts

Testing the efficacy of genomic base editing in dystrophic epidermolysis bullosa primary fibroblasts...