Chemoprevention of RDEB SCC
Chemoprevention of recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma...
29 October, 2025
Archive
29 January, 2025
mRNA-based base editing
Evaluation of long-term effect on skin homeostasis and regeneration in a RDEB mouse model ...
29 January, 2025
Bespoke Therapy for RDEB
This study endeavours to develop personalised therapies for individuals diagnosed with RDEB. ...
21 November, 2024
Base & Prime Editing for RDEB
The project aims to develop a strategy that could be used to treat a significant subset of RDEB patients carrying selected mutations....
23 July, 2024
Gene & Cell Therapy in RDEB SCC
Patients with RDEB are at an increased risk of an aggressive squamous cell carcinoma (SCC) which is usually fatal. This project aims to use modified immune cells which could be given to EB-SCC patients to seek and destroy cancer cells, without effects on healthy tissue....
22 January, 2024
Spray-on-Skin
Study of the Safety, Tolerability, and Efficacy of an iPS Cell-based Therapy for RDEB...
13 December, 2023
PASTE gene therapy in DEB
PASTE-Mediated Superexon Replacement of COL7A1 as a Treatment for Dystrophic Epidermolysis Bullosa...
13 December, 2023
siRNA interference in EBS
siRNA-mediated allele-specific inhibition of mutant KRT5 and KRT14 transcripts in EBS...
30 March, 2023
Exon Skipping Approach to RDEB
Exon skipping approach to RDEB, with the aim to create a shorter but functional Collagen VII protein....
01 September, 2022
Editing of RDEB fibroblasts
Testing the in vivo efficacy of base and prime editing in primary fibroblasts and in a 3D skin model of dystrophic epidermolysis bullosa...